|
|
N-1-(5'-phosphoribosyl)-ATP + H2O <=> 1-(5-phosphoribosyl)-AMP + diphosphate + H+
|
3.6.1.31
phosphoribosyl-ATP diphosphatase
|
–
|
|
BRENDA:
BR22771
KEGG:
R04035
MetaCyc:
HISTPRATPHYD-RXN
|
|
|
|
N'-[(5'-phosphoribosyl)formimino]-5-aminoimidazole-4-carboxamide_ribonucleotide <=> phosphoribulosylformimino-AICAR-phosphate
|
5.3.1.16
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
|
–
|
|
BRENDA:
BR225;
BS1029
KEGG:
R04640
MetaCyc:
PRIBFAICARPISOM-RXN
SABIO-RK:
4302
|
|
|
|
L-histidinal + NAD+ + H2O <=> H+ + L-histidine + NADH
|
1.1.1.23
histidinol dehydrogenase
|
–
|
|
BRENDA:
BS187855
KEGG:
R01163
MetaCyc:
HISTALDEHYD-RXN
|
|
|
|
N-1-(5'-phosphoribosyl)-ATP + diphosphate <=> ATP + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.17
ATP phosphoribosyltransferase
|
–
|
|
BRENDA:
BR47479
KEGG:
R01071
MetaCyc:
ATPPHOSPHORIBOSYLTRANS-RXN
|
|
|
|
L-Histidinol + NAD+ <=> H+ + L-histidinal + NADH
|
1.1.1.23
histidinol dehydrogenase
|
–
|
|
BRENDA:
BS371011
KEGG:
R03012
MetaCyc:
HISTOLDEHYD-RXN
|
|
|
|
D-erythro-1-(imidazol-4-yl)glycerol_3-phosphate <=> 3-(Imidazol-4-yl)-2-oxopropyl_phosphate + H2O
|
4.2.1.19
imidazoleglycerol-phosphate dehydratase
|
–
|
|
BRENDA:
BR404
KEGG:
R03457
MetaCyc:
IMIDPHOSDEHYD-RXN
|
|
|
|
L-Histidinol_phosphate + 2-oxoglutarate <=> 3-(Imidazol-4-yl)-2-oxopropyl_phosphate + L-glutamate
|
2.6.1.9
histidinol-phosphate transaminase
|
–
|
|
BRENDA:
BR47443
KEGG:
R03243
MetaCyc:
HISTAMINOTRANS-RXN
SABIO-RK:
3064
|
|
|
|
L-Histidinol_phosphate + H2O <=> L-Histidinol + phosphate
|
3.1.3.15
histidinol-phosphatase
3.1.3.2
acid phosphatase
|
–
–
|
|
BRENDA:
BR19199
KEGG:
R03013
MetaCyc:
HISTIDPHOS-RXN
|
|
|
|
phosphoribulosylformimino-AICAR-phosphate + L-glutamine <=> H+ + L-glutamate + D-erythro-1-(imidazol-4-yl)glycerol_3-phosphate + 5-aminoimidazole-4-carboxamide_ribonucleotide
|
2.4.2
4.3.1.B2
4.3.2.10
imidazole glycerol-phosphate synthase
|
–
–
–
|
|
BRENDA:
BR51141;
BR52465
KEGG:
R04558
MetaCyc:
GLUTAMIDOTRANS-RXN
SABIO-RK:
4234
|
|
|
|
1-(5-phosphoribosyl)-AMP + H2O <=> N'-[(5'-phosphoribosyl)formimino]-5-aminoimidazole-4-carboxamide_ribonucleotide
|
3.5.4.19
phosphoribosyl-AMP cyclohydrolase
|
–
|
|
BRENDA:
BR26113
KEGG:
R04037
MetaCyc:
HISTCYCLOHYD-RXN
|
|